[Antisteroidal and antigonadotrophic effects of gossypol acetic acid in rats].
摘要
Gossypol acetic acid exhibited an inhibitory effect on the uterotrophic action of estradiol in ovariectornized rats. It also inhibited the progesterone-induced deciduoma in castrated rats.Immature male rats were given hCG 5 I U with or without gossypol acetic acid 20-40 mg/kg daily for 10 days. The steroidogenic response of rat testis to hCG was reduced by gossypol acetic acid.Gossypol acetic acid exhibited a direct inhibitory effect on testosterone production by Leydig cells in vitro. The steroidogenic response of Leydig cells to hCG was also inhibited.
引用本文（GB/T 7714）
Wang Ng, Li Hp, Song Mz, 等. [Antisteroidal and antigonadotrophic effects of gossypol acetic acid in rats].[J]. PubMed, 1984.
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