[Expression of BP1 gene in adult acute leukemia].

Hui Li、Kailin Xu、Xiu-Ying Pan、Haiyan Wang、Zhenyu Li

2004PubMedBiochemistry, Genetics and Molecular Biology被引 1

摘要

OBJECTIVE: To explore the expression of beta protein 1 (BP1) gene in adult acute leukemia (AL) and its relationship with acute leukemia. METHODS: Expression of BP1 gene mRNA was detected in 70 adult AL, 10 normal controls and HEL cell line, by reverse transcriptase-polymerase chain reaction (RT-PCR). RESULTS: No detectable BP1 gene was found in peripheral blood or bone marrow cells of normal controls and 20 acute myeloid leukemia (AML) in complete remission (CR) stage. BP1 gene was highly expressed in HEL cell line, 57% (20/35) of AML and 80% (8/10) of AML-M(5) cases. BP1 gene could not be detected in adult acute lymphoid leukemia. CONCLUSION: BP1 gene was highly expressed in AML. It might be used as a molecular marker of AML.

引用本文（GB/T 7714）

Hui Li, Kailin Xu, Xiu-Ying Pan, 等. [Expression of BP1 gene in adult acute leukemia].[J]. PubMed, 2004.

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