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Progress on amphiphilic polysaccharide self-assembly micelle delivery system

Yan Xue-fe

2014Biochemistry, Genetics and Molecular Biology被引 1

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摘要

Natural polysaccharides are a kind of hydrophilic polymers.By grafting hydrophobic moieties to the polysaccharide backbone,could form self-assembled micelle with core-shell structure in aqueous by undergoing intramolecular or intennolecular association between hydrophobic moieties.The self-assembly micelles of amphiphilic polysaccharides provides a positive outlook for drug delivery systems with biodegradability,low antigenicity,good biocompatibility and so on.This review focus on biological activity of amphiphilic polysaccharide as self-assembly carriers,the principle of self-assembly of polymeric micelles,and the recent progress in hydrophobic modification of natural polysaccharides.

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Yan Xue-fe. Progress on amphiphilic polysaccharide self-assembly micelle delivery system[J]. 未知来源, 2014.

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