一种基于集总参数的心血管系统仿真模型及心音产生机理
摘要
This paper presents a lumped-parameter cardiovascular simulation model based on related basic theories of fluid mechanics and electric network. This model has three sub-models: systemic circulation sub-model, pulmonary circulation sub-model and heart sub-model. We study the systemic circulation sub-model and heart sub-model and give the blood flow parameters and the mechanism of heart sounds, such as simulation waveform, systolic pressure, diastolic pressure, the ejection fraction, etc. Based on these studies, the lumped-parameter cardiovascular simulation model is constructed by integrating pulmonary circulation sub-model, blood vessels, coupled walls, etc. into the systemic circulation sub-model. We build the formula of this simulation model using state variable analysis, and obtain the results of ventricular-atria blood volume, ventricular-atria pressure and artery blood flow. The model is also used to simulate the cardiovascular system under hypertension and heart failure conditions. The simulation results indicate that the cardiovascular simulation is practical feasibility.