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范可尼贫血症与DNA交联损伤修复

Jun HuangJinhua HanTing LiuChunYan RUAN

2014Scientia Sinica VitaeBiochemistry, Genetics and Molecular Biology被引 2

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摘要

Fanconi anemia (FA) is a multigenic recessive disorder caused by mutations in 15 FA or FA-like genes and deficiency in any of these genes renders cells hypersensitive to DNA interstrand cross-linking (ICL) agents. In this review, we summarise our current knowledge about how these FA proteins participate in ICL repair.

引用本文(GB/T 7714)

Jun Huang, Jinhua Han, Ting Liu, 等. 范可尼贫血症与DNA交联损伤修复[J]. Scientia Sinica Vitae, 2014.

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DOI:https://doi.org/10.1360/052014-51

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