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Marchiafava-Bignami Disease: CT,MRI and 99m Tc HMPAO-SPECT Findings

Chu-Jen Kuo、Liang‐Kuang Chen、Huiling Peng、Chin‐Chu Wu

2004Medicine被引 1

摘要

We report neuroimaging studies of Marchiafave-Bignami disease (MBD) diagnosed on a 39-year-old alcoholic man with acute clinical deterioration. Initially, cranial CT and MRI demonstrated diffusely edematous change from the genu to the splenium of the corpus callosum (CC) characteristic for acute stage of MBD. Decreased blood perfusion in bilat-eral parietal and occipital lobes was also noted in SPECT study. Prompt treatment with thiamine and vitamin B comples resulted in clinical improvement. 8 months later, follow-up MR imaging showed typ-ical features of chronic MBD—atrophy with cystic change in the CC. To our knowledge, this is the first case of MBD reported in Taiwan literature.

引用本文（GB/T 7714）