Campylobacter Pylori, Gastritis and Peptic Ulceration
摘要
To evaluate the relationship between C. pylon and gastritis and peptic ulcer disease in our patients, we used Olympus GIF-P10 panendoscopy to examine 95 symptomatic cases and 17 asymptomatic patients who had not been prescribed H2 receptor antagonist, antibiotics or bismuth-containing drugs for 2 weeks. Four antral biopsies were obtained from the antrum, one for urease test and 3 for histopathological studies (HE and Warthin-Starry silver stain). The prevalence of C. pylon infection increases with age. All 95 symptomatic patients contracting chronic gastritis and C. pylon were associated with active chronic gastritis and the infection rate was 61%. The correlation percentage between C. pylon and duodenal ulcer, gastric ulcer, and gastritis was 81%, 56%, and 47%, respectively. Asymptomatic patients showed 35% of C. pylon infection there was statistically significant difference compared with the data obtained from the 95 symptomatic cases. (p＜0.05). Unease test shows 97% sensitivity, 65% specificity and 85% accuracy according to Warthin-Starry silver stain. Prolonged urease reaction time indicated less degree of inflammation. The strong relation between C. pylon and duodenal ulcer disease (81%) was of great clinic interest. Further study is needed before the clinical relevance of C. pylon can be assessed.