Magnetic Resonance Imaging of Rhabdomyolysis: Muscle Necrosis Versus Ischemia
摘要
Rhabdomyolysis is a syndrome caused by injury to skeletal muscle involve, leakage of large quantities of potentially toxic substances into plasma made by laboratory evaluation, Although rhabdomyolysis is seldom discussed on magnetic resonance imaging (MRI), the specific presentation of rhabdomyolysis on MRI can be used as a tool in differencing various etiologies of myopathies but also to evaluate the distribution and extent of injury of affected muscles, Two distinct imaging types of rhabdomyolysis can be distinguished in the initial of diagnosis, i.e. type 1, homogeneous signal changes and contrast enhancement in the affected muscles, signified an ischemic or reversible ischemic reaction, and type 2, homogeneous or heterogeneous signal changes and rim enhancement, and might presence of ”stipple sign” in the affected muscle on contrast-enhanced images, signified an irreversible muscular necrosis. However, to our best knowledge, the imaging-histological correlation that indicated the affected muscles were reversible (ischemia) or irreversible (necrosis) was not reported. We present a case of rhabdomyolysis demonstrating both typical type I and type 2 signal changes on the initial MRI, and complete remission of signal changes in type 1 lesion (ischemia), and persistence of type 2 lesions (necrosis) on follow-up MRI after 3 months and 6 months.