Mucinous Adenocarcinoma of the Renal Pelvis: An Analysis of 5 Cases
摘要
OBJECTIVES: Mucinous adenocarcinomas are a rare lesion of the renal pelvis. We present our clinical experience with this disease at Changhua Show-Chwan Memorial Hospital. MATERIALS AND METHODS: We reviewed the medical records of patients presenting with renal pelvic tumors from 1987 to 2007, and identified 5 cases of mucinous adenocarcinoma. Clinical data including age, gender, clinical presentations, laboratory data, concomitant disease, treatment, and outcomes were retrospectively analyzed, and the histopathological diagnoses were confirmed by a single pathologist. RESULTS: The incidence of mucinous adenocarcinoma of epithelial tumors of the renal pelvis in our hospital was 1.4% (5/349). The mean age of these 5 patients, all men, was 69.6 (range, 64~79) years. All patients had renal stones, and 4 patients had hydronephrosis with or without chronic pyelonephritis. Urinalysis confirmed mucin in the urine of 3 patients (60%). Two of the 5 patients (40%) died of a mucinous adenocarcinoma within 3 years of their diagnosis. CONCLUSIONS: Early diagnosis of mucinous adenocarcinoma is difficult, and clinical presentations are usually nonspecific. Mucin in the urine might be a sign of this disease, especially in patients who also have chronic irritation of the renal pelvis.