Acinar Cell Carcinoma of the Pancreas: Report of a Case
摘要
Acinar cell carcinoma of the pancreas is a rare neoplasm, accounting for about 1% of pancreatic exocrine tumors. In literature, males outnumbered females. Presenting symptoms, compared with ductal adenocarcinoma, were nonspecific. We reported a case of pancreatic tumor in a 23-year-old woman, who presented as a prominent abdominal mass with jaundice. Laboratory data showed elevation of bilirubin, lipase and CA19-9. Image study including ultrasound and computerized tomography revealed an encapsulated tumor arising from pancreas with common bile duct compression. After operation, acinar cell carcinoma was proved by pathology. The tumor, measuring about 11X 10X 8cm in size, looked fleshy and relatively circumscribed grossly. Microscopically, high cellularity without desmoplastic stroma were noted. Besides, typical acinar and solid patterns of growth were identified with characteristic diastase resistant periodic acid-Schiff staining. The differential diagnosis included islet cell tumor, solid and papillary epithelial neoplasm, pancreatoblastoma and so on.