Effect and Influence Factors on Sudden Deafness by Different Treatments
摘要
AIM: To study the curative effect of different treatments and influence factors on sudden deafness (SD). METHODS: Eighty-four cases (89 ears) were divided into three groups: group Ⅰ, group Ⅱ and group Ⅲ had 24 cases (28 ears), 33 cases (34 ears) and 27 cases (27 ears) respectively. Group Ⅰ was treated with vasodilating medicines, reducing blood viscosity agent and neurotrophic agent for inner ear, group Ⅱ was added polarized liquid. The intravenous drip method of medicines and hyperbaric oxygenation (HBO) was used in group Ⅰ and Ⅱ. Nimodipine or flunarizine was given by oral administration. Red sage root injection was given through muscle and HBO was not used in group Ⅲ. RESULTS: The effective rate of the three groups was 67.8%, 64.7% and 70.4% respectively. The difference of Chi-squwere test was not significant. The type of acoustic curve was the most important factor for curative effect with that of low-frequency two being the highest (84.6%) and high-frequency type the lowest (44.4%). The best effect could be obtained if the treatment began within 7 days after the deafness. The auditory threshold became steady 15 days after treatment in the majority of patients and the curative effect rate was 50.8% and 84.7% respectively. The audition was improved 30 days after treatment in a few patients. CONCLUSEON: Difference of the curative effect has no significance in three groups of SD patients. Improving microcirculation of inner ear, reducing blood viscosity, and offering neurotrophic agent for inner ear are the principal treatments. HBO and polarized liquid therapy do not increase the curative effect. The most curative effect is obtained when patients received treatment within 7 days, and 15 to 30 days is the appropriate course of SD.