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Determination of the Absolute Configuration of Rohitukine

DongHuiYANGShaoQingCAIYuYingZHAO

2003中国化学快报:英文版Biochemistry, Genetics and Molecular Biology被引 4

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摘要

The absolute configuration of rohitukine, isolated from the stem-bark of Dysoxylum binectariferum, was determined to be 5,7-dihydroxy-2-methyl-8-[4-(3S, 4R-3-hydroxy-1-methyl) -piperidinyl]-4H-1-benzopyran-4-one by X-ray crystallographic analysis on the crystal of 4-bromobenzoyl derivatives of rohitukine. At the same time, the modified Mosher'method was proved to be unsuitable for determining the absolute configuration of C-3’position in rohitukine.

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DongHuiYANG, ShaoQingCAI, YuYingZHAO. Determination of the Absolute Configuration of Rohitukine[J]. 中国化学快报:英文版, 2003.

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