DNA Cleavage of the Copper（II） Complexes with a Polyamine Ditopic Ligand
摘要
A new binuclear complex [Cu2L(OH)](CIO4)3.2H20 has been synthesized andcharacterized, where L=2,6-bis{[bis-(2-aminoethyl)amino]methyl}-benzene. In the presence of 0.5 mmol/L complex at pH 8.10 and 37℃, the complex can efficiently cleavage pBR322 DNA with a rate constant kobs of 1.35×10^-4 S^-1. The cleavage occurred by a non-oxidative mechanism showing activity to be dependent on pH.
引用本文（GB/T 7714）
Yibin Wei, PinYANG. DNA Cleavage of the Copper（II） Complexes with a Polyamine Ditopic Ligand[J]. 中国化学快报：英文版, 2005.
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