Clinical Experience of Pheochromocytoma
摘要
Pheocromocytomas, especially extra-adrenal lesions, can potentially cause lethal complications if they are not recognized. Because of possible unusual locations and lack of classical symptoms or signs, extra-adrenal pheochromocytomas may be easily neglected. A retrospective review of 58 cases of pheochromocytomas showed that 45 cases were adrenal lesions (Group A) and 13 cases were extra-adrenal lesions (Group B). Clinical parameters, e.g., age, sex, symptoms or signs, biochemical data, incidence of malignancy, DNA flow cytometric studies, localization methods were compared. In Group A, the male sex seemed to be more dominant than in Group B. Other clinical parameters were quite compatible in both groups. There was no difference in the incidence of malignancy or results of DNA flow cytometric studies between the groups. Radioactive iodine-labeled metaiodobenzyl-guanidine scan and computed tomography scan seemed to be the best localization methods. With improvement in diagnostic modalities, hagh index of suspicion is still the key in diagnosing extra-adrenal pheochromocytomas. As in their adrenal counterparts, malignanc is possible. Long-term follow-up for these extra-adrenal lesions is essential.