Ichthyosis Hystrix of Curth-Macklin
摘要
Ichthyosis hystrix of Curth-Macklin (IHCM) is an extremely rare keratinization disorder, with verrucous to hystrix-like hyperkeratosis plaques of varying extent. The diagnosis is based on a distinctive pattern of epidermolytic hyperkeratosis and the presence of binucleate cells under light microscopy, as well as unique electron microscopic findings of continuous perinuclear tonofibril shells in the suprabasal keratinocytes. We present the clinical manifestation and light and electron microscopic findings in a 23-year old male patient with IHCM.
引用本文(GB/T 7714)
Hung‐Hsu Yang, Nan‐Lin Wu, Yang‐Chih Lin, 等. Ichthyosis Hystrix of Curth-Macklin[J]. 未知来源, 2004.
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