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光动力学疗法中的单态氧发光检测系统

Buhong LiHuiyun LinDefu ChenMin WangShusen Xie

2010Chinese Optics LettersMedicine被引 14开放获取

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摘要

Singlet oxygen ( 1 O 2 ) is widely considered to play a major role in photodynamic therapy (PDT), and thus an increasing attention has been focused on the direct detection of 1 O2 near-infrared luminescence around 1270 nm for PDT dosimetry. A new sensitive detection system is developed to directly measure the temporal and spectral resolved 1 O2 luminescence spectra. The triplet state and 1 O2 lifetimes of Rose Bengal as a model photosensitizer in different solvents are determined, and the obtained results agree well with the published data. Our detection system has the potential application in 1 O2 luminescence-based PDT dosimetry.

引用本文(GB/T 7714)

Buhong Li, Huiyun Lin, Defu Chen, 等. 光动力学疗法中的单态氧发光检测系统[J]. Chinese Optics Letters, 2010.

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DOI:https://doi.org/10.3788/col20100801.0086

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