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Synthesis and Characterization of Chitosan-g-poly- (D, L-lactic acid) Copolymer

HuaYANGShaobing ZhouXian-moDeng

2005中国化学快报:英文版Materials Science被引 3

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摘要

Biodegradable chitosan-g-poly (D, L-lactic acid) copolymers were prepared via two methods. (1) The lactide was grafted onto hydroxyl groups of chitosan by using macromolecular initiator sodium of trimethylsilyl-chitosan, (2) poly (D,L-lactic acid)(PLA) with low molecular weight can be linked to the amino group by coupling activated PLA to trimethylsilyl-chitosan. Two graft copolymers had hydrophilic-hydrophobic character and can be applied as carriers for drug delivery.

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HuaYANG, Shaobing Zhou, Xian-moDeng. Synthesis and Characterization of Chitosan-g-poly- (D, L-lactic acid) Copolymer[J]. 中国化学快报:英文版, 2005.

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