Transfusion of donor apoptotic splenocytes prolongs cardiac allograft survival in absence of immunosuppression
摘要
Although apoptosis has been recently documented to transmit immunosuppressive signals, their significance in allogeneic transplantation has not been reported. In the present study, we investigated the influence of donor apoptotic splenocytes on allograft survival in a SD to Wistar rat cardiac transplant model. Donor splenocytes were isolated and irradiated with ultraviolet (UV) to induce apoptosis in vitro. 5x107 apoptotic, necrotic or untreated donor spleen cells were transfused preoperatively and cardiac allogeneic transplantation
引用本文（GB/T 7714）
Er-WeiSun, Yufangshi. Transfusion of donor apoptotic splenocytes prolongs cardiac allograft survival in absence of immunosuppression[J]. Acta Scientiarum Naturalium Universitatis Sunyatseni, 2002.
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