[Screening and identifying hepatotoxic components in Aucklandiae Radix with GC-MS].

Xiaoping Zhao、Lin Lü、Bin Hu、Shufang Wang

2012PubMedMedicine被引 4

摘要

OBJECTIVE: To screen the potential hepatotoxic components in Chinese herb medicine Aucklandiae Radix. METHODS: The potential hepatotoxic components were screened using HepG2 cells labeled with fluorescein diacetate from 25 fractions of Aucklandiae Radix, in which the hepatotoxic compounds were further identified with GC-MS. RESULTS: Ten potential hepatotoxic fractions were screened. The identification results by GC-MS indicated that the main compounds in C09 were dehydrocostuslactone, santamarine (or magnolialide) and reynosin, and in C11 were α-costol and elemol. CONCLUSION: Dehydrocostuslactone, santamarine (or magnolialide), reynosin, α-costol and elemol are potential hepatotoxic compounds in Aucklandiae Radix.

引用本文（GB/T 7714）

Xiaoping Zhao, Lin Lü, Bin Hu, 等. [Screening and identifying hepatotoxic components in Aucklandiae Radix with GC-MS].[J]. PubMed, 2012.

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DOI：https://doi.org/10.3785/j.issn.1008-9292.2012.01.007

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