Synthesis of a Dopamimetic Thionated Dipeptide Prodrug of L-DOPA
摘要
L-DOPA has gained widespread credit over the past decades as being the mainstay of the pharmacological treatment of Parkinson's disease. However, there are many adverse effects associated with the use of L-DOPA. The prodrug approach is the most promising way to solve the problem. In this article, a thionated dipeptide prodrug of L-DOPA 11 was synthesized via 10steps in a total yield of 26.5% from L-DOPA.
引用本文（GB/T 7714）
YeWANG, ZhanZhuLIU, ShiZhiCHEN. Synthesis of a Dopamimetic Thionated Dipeptide Prodrug of L-DOPA[J]. 中国化学快报：英文版, 2005.
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