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Formation of a potential tumor therapeutic pharmaceutical ^186Re—bleomycin

LUOShun-ZhongDENGHou-Fu

1998Acta Scientiarum Naturalium Universitatis SunyatseniMedicine被引 2

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摘要

The influence of experimental conditions on the formation of 186Re-bleomycin (BLM) was studied.The results show that the labeling yield is mainly dependent on the pH value in reaction medium and gluconate can effectively protect the re-oxidation of Re reduced by sn(II),A better method for preparing ^186Re-BLM is described with labeling yield up to 95% in the pH range from 3.0 to 4.5.

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LUOShun-Zhong, DENGHou-Fu. Formation of a potential tumor therapeutic pharmaceutical ^186Re—bleomycin[J]. Acta Scientiarum Naturalium Universitatis Sunyatseni, 1998.

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