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Synthesis of C-Nucleoside Analogues: 2-[2-(Hydroxymethyl)-1, 3-dioxolan-5-yl]1, 3-thiazole-4-carboxamide and 2-[2-(Mercaptometh-yl)-1, 3-dioxolan-5-yl] 1, 3-thiazole-4-carboxamide

DongMeiCAIMinJieLIDaLiangLITianPaYOU

2004中国化学快报:英文版Biochemistry, Genetics and Molecular Biology被引 3

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摘要

Novel C-nucleosides of tiazofurin analogue (2-[2-(hydroxymethyl)-1,3-dioxolan-5-yl] 1,3-thiazole-4-carboxamide) and its thiol-substituted derivative (2-[2-(mercaptomethyl)-1,3-dioxolan-5-yl] 1, 3-thiazole-4-carboxamide) were synthesized from methyl acrylate through a multistep procedure. Their structures were confirmed by IR, ^1HNMR, ^13CNMR and elemental analysis.

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DongMeiCAI, MinJieLI, DaLiangLI, 等. Synthesis of C-Nucleoside Analogues: 2-[2-(Hydroxymethyl)-1, 3-dioxolan-5-yl]1, 3-thiazole-4-carboxamide and 2-[2-(Mercaptometh-yl)-1, 3-dioxolan-5-yl] 1, 3-thiazole-4-carboxamide[J]. 中国化学快报:英文版, 2004.

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