精神病医院门诊苯二氮(艹卓)类药物使用情况分析
摘要
Objective: To understand the use of benzodiazepines (BDZ) in a mental health hospital. Methods: An analysis of 6472 prescriptions which were randomly selected from the prescriptions prescribed from January 2005 to December in the Psychiatric Hospital of Tongji Medical College was conducted with daily defined dose (DDD) and drug utilization index (DUI). Results: Among 6472 prescriptions, 1824 (28.18%) included BDZ. They were clonazepam (43.04%), alprazolam (25.0%), diazepam (16.67%), estazolam (9.70%), nitrazepam (5.04%) and lorazepam (0.55%). The DUI of diazepam, nitrazepam and lorazepam was a little less than 1, while the DUI of clonazepam, alprazolam and estazolam was more than 1. The prescriptions lasted over four weeks and more than twelve weeks accounted for 60.42%and 8.33%, respectively. The longest duration was 150 days. Conclusion: It is not obvious that doctors in this hospital abuse BDZ, but there exist some problems.